Our Research

AIDS Clinical Trial Group (ACTG)

ACTG develops and conducts translational research and clinical trials to a) investigate the viral and immune pathogenesis of HIV infections and its complications; b) evaluate novel drugs and strategies for testing HIV infection; c) evaluate interventions and strategies to treat and prevent HIV-related co-infections and co-morbidities; and d) publish and disseminate results to improve care and reduce or eliminate morbidity and mortality associated with HIV infection and its complications.
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HIV Prevention Trials Network (HPTN)

HPTN seeks to develop and test the safety and efficacy of interventions designed to prevent the acquisition and transmission of HIV. The HPTN research agenda is focused primarily on the use of integrated strategies that include a) use of antiretroviral drugs (antiretroviral therapy and pre-exposure prophylaxis); b) interventions for substance abuse, particularly injection drug use; c) behavioral risk reduction intervention and structural interventions.
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HIV Vaccine Trials Network (HVTN)

HVTN seeks to fully characterize the safety, immunogenicity, and efficacy of HIV vaccine candidates with the goal of developing a safe, effective vaccine as rapidly as possible for prevention of HIV infections globally.
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International Maternal Pediatric Adolescent AIDS Clinical Trials Group (IMPAACT)

IMPAACT evaluates potential therapies for HIV infection and its sequelae in the infant, pediatric, adolescent, and pregnant women populations, including a) the pharmacokinetics and safety of new ARV treatments and formulations; b) using ARV agents and novel treatment strategies to investigate HIV pathogenesis and the reconstitution of the immune system; c) interventions to prevent mother-to-child HIV transmission in the perinatal period and breastfeeding; d) the safety, immunogenicity, and efficacy of licensed childhood vaccines and novel non-HIV vaccines in HIV-infected youth; and e) assessing optimal therapy for women over the course of their lifetime.
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Microbicide Trials Network (MTN)

MTN integrates both biomedical and behavioral science in the design and implementation of clinical trials, looking at the safety, effectiveness, acceptability, and adherence involving a range of different vaginal and rectal microbicide products for HIV prevention. MTN’s research agenda includes populations considered among those at highest risk, including women, adolescents, and pregnant and breastfeeding women.
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Non-Network Research

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