International Neuropsychological Assessment of Patients Initiating Antiretroviral Therapy in Resource-Limited Settings

US National Institute of Allergy and Infectious Diseases (NIAID)
US National Institute of Mental Health

A5199 was a prospective, observational, international, multicenter study of cognitive impairment and dementia due to HIV (AIDS dementia complex [ADC]) and HIV-associated neurological opportunistic infections in participants with advanced disease in resource-limited settings who are enrolled in A5175

Years: 2005 – 2009

Investigator: James Hakim, MBChB, FRCP

Location: Parirenyatwa CRS


Completed Study


Robertson K, Jiang H, Kumwenda J, Supparatpinyo K, Evans S, et al. (2012) Improved neuropsychological and neurological functioning across three antiretroviral regimens in diverse resource-limited settings: AIDS Clinical Trials Group study A5199, the International Neurological Study. Clin Infect Dis 55(6): 868-76.

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